The science

A novel, multi-modal approach to Weight Loss.

Appetec was founded on a simple premise: lasting weight management works best when it addresses the body, the gut, and the mind together. Our platform combines non-invasive gastric vibrational therapy with AI-driven adaptive coaching — targeting both the physiological and behavioral roots of obesity.

Presented at the IBC Oxford World Congress · September 2025 · Shahriar Sedghi, MD, AGAF — Mercer University School of Medicine, Appetec founder

The problem

Current obesity treatments fall short

Despite widespread use, existing treatments for obesity have consistent limitations. Lifestyle changes are hard to sustain, behavioral therapies show mixed long-term results, medications face high dropout rates, and even bariatric surgery — the most effective intervention available today — often fails to prevent long-term weight regain.

GLP-1 medications

32%

of users remained on therapy after one year; only 17% consistently adherent by year two.

Gastric bypass

50%

of patients regained weight within 24 months of surgery; 37% saw significant regain by year seven.

Gastric sleeve

76%

of patients experienced significant weight regain within six years of the procedure.

Sources: Bennett & Sothern, Semin Pediatr Surg (2009); Foreyt et al., J Behav Med (1981); Blue Cross Blue Shield of Kansas (2025); Madura & DiBaise, F1000 Med Rep (2012); Magro et al., Obes. Surg. (2008); Cooper et al., Obes. Surg. (2015); Lauti et al., Obes. Surg. (2016); King et al., JAMA (2018).

Our answer

Physiology + behavior, together

Gastric Vibrational Therapy (GVT) — a non-invasive, wearable device that uses precisely calibrated vibration to engage the body’s natural fullness signals. No surgery. No injections. No downtime.

Adaptive AI coaching — a mobile app grounded in cognitive behavioral therapy that learns from your mood, hunger, sleep, and activity patterns to deliver timely, personalized guidance in the moments that matter most.

Prebiotic nutrition — a daily fiber supplement that supports gut health as part of a balanced, sustainable routine.

Early pilot results

Meaningful weight loss

Appetec’s early pilot published research showed encouraging results. Independent research has shown significantly decreased food intake in pigs subjected to vibration treatment.

Peer-reviewed foundations

Every product decision is anchored in published research and measurable outcomes.

Expanding clinical studies

Building on pilot outcomes with larger, longer-term investigations of the GVT platform.

Transparent methodology

Full study results and references will be published as they become available.